The womenshealth.gov website mentions these no-medication possibilities:

• Practicing relaxation and breathing techniques.
• Relaxing in a warm shower or bath, or getting a gentle massage.
• Receiving hot and cold therapy, including placing a cool washcloth on the forehead or a heating pad on the lower back.
• Seeking the care and support of a doula, nurse or loved one.
• Trying various positions to get more comfortable, from crouching to walking.
• Listening to soothing music.
• Using a labor ball.

-- Diana Kohnle